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Narrative Summary of Recently Published Literature on Intravenous Ibuprofen

Dr. Stephen Southworth of Orthopaedic of North Mississippi Clinic

Narrative Summary of Recently Published Literature
														on Intravenous Ibuprofen

Opioids are well tolerated and inexpensive when used appropriately; however, dependence, misuse, and diversion of opioids have resulted in a tsunami of overdose-related deaths in the United States. While accounting for only 5% of the world's population, the United States accounts for 80% of oxycodone use and 99% of hydrocodone use. Opioid overdoseerelated deaths exceed traffic collisionerelated deaths in the United States.

Orthopedic Surgeon Leader To Know:

Dr. Stephen Southworth of Orthopaedic of North Mississippi Clinic

Stephen Southworth, MD, is an orthopedic surgeon at Orthopaedic Institute of North Mississippi Clinic, a multi-office practice with four locations throughout the state. Dr. Southworth specializes in the treatment of osteoarthritis, with an emphasis on ankle, hip and knee replacement.

An Integrated Safety Analysis Of Intravaneous Ibuprofen (CALDOLOR®) In Adults

Dr. Stephen R. Southworth

Ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID) with a well known and long history of use. Oral ibuprofen was approved in the USA over 40 years ago and has been a nonprescription drug for more than 30 years. IV ibuprofen (CaldolorĀ®, Cumberland Pharmaceuticals Inc., Nashville, TN, USA) was first approved in 2009 for the management of mild to moderate pain, moderate to severe pain in conjunction with narcotics, and for the reduction of fever in adults.